Managing PCOS Symptoms by Reducing Androgens
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237.8K views1 year ago
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Facial hair (hirsutism) in PCOS is driven by androgen activity at the hair follicle, not just the absolute amount of androgens circulating in blood. So even if blood tests (like total/free testosterone, DHEAS, androstenedione) are within the normal lab range, there can still be increased local androgen effect in the skin. 👉🏻Increased sensitivity of hair follicles to androgen Some women have more active 5-α reductase enzyme in hair follicles, which converts testosterone → dihydrotestosterone (D
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