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Aridiane Costa | Dilui Farma on Instagram: "🫀 Por que AAS + Clopidogrel no infarto? (Farmacologia clínica) No infarto (SCA), o problema central é a formação rápida de um trombo plaquetário sobre uma placa instável. 🔹 AAS (ácido acetilsalicílico) • Inibe irreversivelmente a COX-1 • ↓ produção de tromboxano A₂ • Resultado: ↓ agregação plaquetária 🔹 Clopidogrel • Inibe o receptor P2Y12 do ADP na plaqueta • Bloqueia ativação e agregação plaquetária dependente de ADP 🔹 Por que usar os dois juntos
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