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When the COVID-19 vaccines were created there were two main goals: First, the vaccine needed to be safe to administer to the general population. Second, the vaccine needed to be efficacious against the pathogen. There are a couple ways to identify that - by seeing if it produces a significant immune response to the virus or by seeing if it reduces the chance of getting the disease itself. Once the candidate vaccines were created they entered human trials where the drug was tested for safety and
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