Huntington's disease – the two faces of a deadly mutation 🧠 #naturopath #medicine
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Huntington's disease – the two faces of a deadly mutation 🧠 #naturopath #medicine
Eine einzige mutierte Genkopie reicht aus, um die Erkrankung auszulösen – autosomal-dominant vererbt, mit 50 % Risiko für jedes Kind. Ursache ist eine CAG-Repeat-Expansion im HTT-Gen. Ab etwa 40 Wiederholungen entsteht ein verlängertes Huntingtin-Protein, das sich fehlfaltet, Nervenzellen schädigt und besonders das Striatum zugrunde gehen ...
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