Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular reocclusion may occur after intravenous thrombolysis and may be preventable ...

The author describes the scientific foundations and implications of a study on variant EPO and erythrocytosis.

After decades of undergoing epidemiologic study, prostate cancer remains an enigmatic disease; the only established risk factors are older age, family history of prostate cancer, and African ancest ...

In 2006, a prospective observational study first showed that physical activity after a colon cancer diagnosis was linked to a decreased risk of recurrence and death.1 Since then, numerous observati ...

The U.S. Supreme Court recently upheld Tennessee’s ban on gender-affirming hormonal treatment for transgender minors. This decision will have profound implications.

The financial assistance policies of some U.S. hospitals now define medical necessity much more restrictively than it has conventionally been understood, as covering only services that are ...

New AI-based software for generating patient notes purposely filters out social “chitchat,” but a primary care physician sees serious risks in that practice, for doctors and patients alike.

A 70-year-old man with benign prostatic hyperplasia was seen for worsening lower urinary tract symptoms and new-onset hematuria. A radiograph of the pelvis showed an irregularly shaped, radiopaque ...

This editorial explains the genetic basis of Pompe’s disease and other lysosomal storage disorders, as well as the foundations of enzyme-replacement therapy.

The landscape for genetically modified organisms is changing, thanks to sharp increases in the amounts and numbers of chemical herbicides applied to GM crops and the classification of two of the mo ...

A 60-year-old man with hypertension and bipolar disorder was incidentally found to have small cysts on his kidneys during MRI of the abdomen.