The San Francisco 49ers cannot last more than a few months without losing their entire running back room to injury, even in ...

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

The 49ers likely have no intention of playing starter Christian McCaffrey in the preseason, backup Isaac Guerendo is out for ...

The 49ers saw top draft pick Mykel Williams exit with a hyperextended knee in their spirited joint practice with the Denver ...

The 49ers may provide an indication of how they're feeling about their RB depth in the days ahead. If they sign another ...

After the Broncos’ frontmen pillaged San Francisco, Castle Rock native and 49er Christian McCaffrey confirmed what Denver’s ...

The 49ers are hoping to rebound from a lost season in 2024 and Christian McCaffrey's return from injury will be a major boost ...

The 49ers are limiting Christian McCaffrey's training camp reps to keep the running back healthy for the season opener and ...

Mackenzie Brooks and the Inside the Lines Team break down where every NFC West team's season is most likely to end and how to ...

San Francisco's Christian McCaffrey revealed the unteachable traits that make 49ers QB Brock Purdy "so special." ...

Christian McCaffrey has some dad guilt as football preseason heats up. The San Francisco 49ers running back has been busy in ...

This is the second installment on fantasy drafting. Today it's running backs. (Find my article on wide receivers here.) There are more good receivers than running backs—and/or there is an earlier and ...