The 49ers likely have no intention of playing starter Christian McCaffrey in the preseason, backup Isaac Guerendo is out for ...

The San Francisco 49ers could use more capable running backs on their roster and signing Jeff Wilson Jr. gives them another.

The San Francisco 49ers are reportedly bringing back a familiar face to an injury-depleted backfield. Jeff Wilson Jr., who ...

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

The San Francisco 49ers cannot last more than a few months without losing their entire running back room to injury, even in the preseason. With multiple key players back on the shelf, the 49ers added ...

The 49ers saw top draft pick Mykel Williams exit with a hyperextended knee in their spirited joint practice with the Denver ...

The 49ers may provide an indication of how they're feeling about their RB depth in the days ahead. If they sign another ...

A year ago it was either Brandon Allen or Joshua Dobbs behind Purdy, and it didn’t turn out well for the 49ers.

The 49ers are limiting Christian McCaffrey's training camp reps to keep the running back healthy for the season opener and ...

The 49ers are hoping to rebound from a lost season in 2024 and Christian McCaffrey's return from injury will be a major boost ...

Two top contenders this year face off in the preseason opener, with the San Francisco 49ers hosting the Denver Broncos. However, many fans are wondering whether stars Christian McCaffrey and Bo Nix ...

Christian McCaffrey has some dad guilt as football preseason heats up. The San Francisco 49ers running back has been busy in ...