136 Real-world evidence comparing the vitamin-K-antagonist phenprocoumon versus direct oral anticoagulants in patients with atrial fibrillation in Germany ...

Methods The ‘implementation gap’ refers to the difference between the evidence of what works in theory and what is actually delivered in practice. A suite of integrated implementation measures was ...

Most physical tests to identify lumbar-disc herniation show poor diagnostic performance when used in isolation, but findings may not apply to primary care ...

This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RRs) use modified systematic review methods to accelerate the review process ...

This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RR) use modified systematic review methods to accelerate the review process ...

Clinical trials reduce uncertainties about the benefits and harms of an intervention. Outcomes of interest should be specified before the trial starts (a priori), and clinically relevant to patient ...