A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life ...
Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...
A study has traced thousands of conserved regulatory elements back 300 million years, revealing deep principles of plant ...
Researchers have discovered that mutations in the FOXJ3 gene act as a "master switch" failure, disrupting how the brain ...
A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new approach to drug discovery that has already yielded some promising ...
Trained on 9 trillion DNA base pairs from every domain of life, the Evo 2 model can predict disease-causing mutations, ...
Researchers have created a method called optovolution that uses light to guide the evolution of proteins with dynamic behaviors. By engineering yeast cells so their survival depended on proteins ...
Drug-resistant epilepsy affects millions worldwide, with focal cortical dysplasia (FCD) as one of the leading causes. Yet its ...
Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and biomarker discovery in proteomics.
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