Signalling by bone morphogenetic proteins (BMPs) acts in a conserved all-or-none fashion to repress the expression of all neural genes in the epidermal ectoderm of bilaterian embryos. The ...

Frizzled (Fz)/planar cell polarity (PCP) signalling is a conserved mechanism regulating the polarity of cells along the axes of a tissue. Fz/PCP regulates a diverse array of processes including the ...

This manuscript uncovers the importance of Vinculin in the maintenance of junctional integrity during neural tube closure in regions of increased mechanical stress, by using sophisticated methods such ...