Pathogenic activating point mutations in the LRRK2 kinase cause autosomal-dominant familial Parkinsońs disease (PD). In cultured cells, mutant LRRK2 causes a deficit in de novo cilia formation and ...

This manuscript describes the impact of modulating signaling by a key regulatory enzyme, Dual Leucine Zipper Kinase (DLK), on hippocampal neurons. The results are interesting and will be important for ...

Dozens of labs around the world are striving to grow models of human embryos to study development, fertility and therapies.

On a sweltering day in July 2023, a ragtag group of data wonks sat around a table at U Zlatého Tygra, or the Golden Tiger, a ...

To assess the potential pathogenicity of WELV, in vivo experimental infections were produced in Balb/c, C57BL/6J, Kunming, and IFNAR1 −/− C57BL/6J mice ... and a 3′-terminus of AGAGUUUCU ...

Good evening from Cardiff – a lovely one here, though it is chilly. The Aussies certainly think so, wearing their beanie hats ...

Culture Night 2024 is almost upon us, with thousands of people set to enjoy a night of rich culture and creativity across the country tomorrow.The late-night annual event follows last year's high ...

Does the Gigabyte Aorus 16X deliver enough gaming performance, or is it lost in a crowd of mid-range mediocrity?

MANILA, Philippines — Up to 10,490 aspiring lawyers completed the three-day Bar examinations, Supreme Court (SC) Associate Justice Mario Lopez announced yesterday. The number is down from the ...

Carter chose these variants based on five criteria: how well the wild-type allele is conserved between people and mice, ...

To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...