Original research: Mortality associated with moderate and severe mitral regurgitation in 608 570 men and women undergoing ...

Background Effective management of coexisting heart failure (HF), chronic kidney disease (CKD) and type 2 diabetes mellitus ...

Following injury, many organs are capable of rapid regeneration of necrotic tissue to regain normal function. In contrast, ...

For over two decades, a ‘treatment-risk paradox’ has been described in older adults with cardiovascular disease, with ...

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components of the internal immune cells, which profoundly affects the internal ...

Implantation of drug-eluting stents (DESs) remains central to percutaneous coronary intervention (PCI) for acute coronary syndromes (ACS) and chronic coronary syndromes (CCS). DES platforms, polymers ...

OBJECTIVE To assess whether the use of inverted lead aVR (−aVR) would improve the classification of acute inferior or lateral myocardial infarction presenting with ST elevation. DESIGN Observational ...

Introduction Pulmonary vein isolation (PVI) is an established therapeutic strategy for atrial fibrillation (AF). Recent advancements in AF ablation have led to the development of the novel pulsed ...

Objective Troponin and B-type natriuretic peptide (BNP) concentrations are associated with cardiovascular risk in stable patients. Understanding their determinants and identifying modifiable clinical ...

Background Pulmonary hypertension (PHT) lacks community prevalence and outcome data. Objective To characterise minimum ‘indicative’ prevalences and mortality data for all forms of PHT in a selected ...

Objective To investigate sex differences in prevalence, treatment and control of major cardiovascular risk factors in England. Methods Data from the Health Survey for England 2012–2017 on ...