This article explores advanced oligonucleotide analysis techniques, including chromatography methods for therapeutic RNA, ...

Ion-exchange chromatography (IEX) is a class of liquid chromatography used to separate organic and inorganic molecules, in particular biomolecules. In this article, we explore how the technique works ...

Isolation of trace impurities and degradants from mixtures containing primarily an API, or an API plus excipients, is often necessary for structure elucidation purposes. Using chromatographic methods ...

TLC principle is well explained with examples. Thin layer chromatography is the easy method to separate different types of chemical molecules from each other with the help of thin layer chromatography ...

Despite all the innovations in liquid chromatographic technology, the principles of chromatography remain unchanged. The factors that affect selectivity and retentivity in HPLC are the same in UPLC.

The rapid advancement of mRNA therapeutics, driven by the success of mRNA-based vaccines, has created an urgent need for robust analytical methods to define and control the critical quality attributes ...

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in ...

LCGC International provides separation science insights, including liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS).

In these methods, boronate or phenyl borate can be used as affinity ligands in combination with agarose or high-performing affinity chromatography (HPAC) methods for the stationary phase.