Cell growth and survival are tightly controlled in multicellular organisms. An important component of this control system in mammalian cells is the p53 tumor suppressor protein (reviewed in Gottlieb ...
Wig-1, also known as ZMAT3, is a p53 target gene that encodes an RNA-binding zinc-finger protein involved in the regulation of mRNA stability through binding to AU-rich elements (AREs). We have used ...
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