One of the greatest mysteries of our planet is how a soup of lifeless chemicals transformed into the first living cell. There are several competing theories about where this happened, from frozen ...
Researchers at the MRC Laboratory of Molecular Biology in Cambridge have discovered a ribozyme that is shockingly small, yet ...
Pharmaceutical Technology on MSN
RNA-targeting small molecules: A new frontier of drug discovery
With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology ...
A mysterious RNA found in breast cancer led scientists to uncover an entire hidden class of cancer-specific RNAs across ...
These random molecules were fed a collection of three-base-long RNAs, each linked to a chemical tag. The idea was that if a molecule is capable of ligating one of these short RNA fragments to itself, ...
A team led by UNC School of Medicine researchers is the first to confirm that a small molecule called miR-29 plays a role in driving aging. Their new findings are published in Communications Biology.
Acid resistance is a crucial property that enterobacteria must possess to withstand host acidic environments during infection, including the gastrointestinal tract and macrophage phagosomes. The ...
WALTHAM, Mass.--(BUSINESS WIRE)--Arrakis Therapeutics, a biopharmaceutical company pioneering the discovery of a new class of small molecule medicines that directly target RNA, today announced that ...
Mammalian immunity has long been thought to rely solely on proteins and specialized immune cells. However, a newly proposed concept—RNA immunity—is reshaping this perspective. In a recent publication ...
RNA immunity is a defense system against viruses, including the cross-species regulation of exogenous miRNAs and the endogenous RNA-based immune system. Figure created with BioRender.com. Conventional ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results