The aim of this paper is to provide an overview of sample size estimations for the most frequent type of group studies that result in continuous, binary and ordered categorical outcomes. In recent ...
Wondering how many people in the United States have a smartphone? If you poll 20 people on the street, your survey won’t be representative of the entire American population. But if you just want to ...
Sample sizes for single-stage phase II clinical trials in the literature are often based on exact (binomial) tests with levels of significance (alpha (α) <5% and power >80%). This is because there is ...
Our latest focus is trying to bring data to bear on common questions we get asked by clients. Last month the topic was: how well does my device need to perform to get premarket clearance from FDA?
Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...
What best distinguishes human beings from other animals is our foresight, so why do we get forecasting so wrong and so frequently, and don’t learn from our mistakes? For example, man is the only ...
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