Poly(ADP‐ribose) polymerases (PARPs) are a family of enzymes that play a crucial role in maintaining genomic integrity by detecting DNA damage and facilitating its repair. By catalysing the covalent ...
In living organisms today, complex molecules like RNA and DNA are constructed with the help of enzymes. So how did these molecules form before life (and enzymes) existed? Why did some molecules end up ...
Impact of body mass index, diabetes, and tumor mutational burden in ovarian, fallopian tube, and primary peritoneal carcinoma with BRCA1/2 alteration on poly(ADP-ribose) polymerase inhibitors. This is ...
Impact of rucaparib on circadian rhythms and adverse events in ovarian cancer: Insights from the MAMOC trial. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does ...