HOW Does 6-PPDQ disrupts the citric acid cycle in caenorhabditis elegans. FAYETTEVILLE, GA, UNITED STATES, July 2, 2025 /EINPresswire / -- Researchers explore how 6-PPD quinone (6-PPDQ), an ...
Pyruvate dehydrogenase plays a critical role in how cells produce energy. The reaction it carries out is the first step in converting pyruvate, which the body derives from food, to acetyl-CoA, a fuel ...
In anaerobic organisms, the decarboxylation of pyruvate, a crucial component of intermediary metabolism, is catalyzed by the metalloenzyme pyruvate: ferredoxin oxidoreductase (PFOR) resulting in the ...
6-PPDQ, has emerged as an environmental concern due to its widespread detection and toxic effects. In a study published in Environmental Chemistry and Ecotoxicology, researchers from Southeast ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, No. 21 (Oct. 15, 1996), pp. 11466-11470 (5 pages) Acetyl-CoA carboxylase, which has a molecular mass of 265 ...
Few building blocks in cellular metabolism are as central and versatile as acetyl-coenzyme A (acetyl-CoA). As a product of many CO 2 fixation pathways, its utilization in the cell determines how much ...
Pyruvate kinase deficiency, the most common genetic lesion in the glycolytic pathway, leads to chronic hemolytic anemia. Mitapivat, an oral agent, can activate some mutant enzymes and restore red-cell ...
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