Mesenchymal drift may help explain how cells lose stable identity and acquire pro-fibrotic, inflammatory mesenchymal traits ...

Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared with individuals without the disease, reports a study ...

Idiopathic pulmonary fibrosis (IPF) is an aging-associated disease caused by progressive scarring of the lungs, leading to respiratory failure and death. Therapies to treat IPF are limited, making ...

Epigenetic aging clocks use DNA methylation patterns to measure biological age and predict health risks across human tissues.

Microglial cells are the maintenance workers of the central nervous system (CNS), protecting against pathogens and pruning damaged neurons to help the brain maintain homeostasis. Considered immune ...

These patients must have had progressive symptoms for fewer than five years and be accompanied by a care partner. Funding: This research is supported by the NIH’s National Institute on Aging ...