Despite being a cornerstone of cancer treatment advancement, clinical trials remain inaccessible for many patients because of structural, socioeconomic, and systemic barriers. In this ...

As rare disease trials face persistent feasibility challenges, Bayesian designs are gaining momentum by enabling more flexible, data-driven approaches that integrate prior knowledge, reduce sample ...

In his Complex Litigation column, Michael Hoenig writes: Presentation of the defendant's case in the modern products liability trial is the major opportunity to set the record straight and demonstrate ...

Michael Hoenig, in his Complex Litigation column, offers practical trial tips on summations, the “final opportunity” to convince the jury that his client should prevail. The trial lawyer seeks to ...

Expert investigators are recommending steps that can remove barriers to participation in cardiovascular clinical trials, with the aim of producing research results that are truly representative.

Bayesian prediction and modeling have emerged as transformative tools in the design and management of clinical trials. By integrating prior knowledge with accumulating trial data, Bayesian methods ...

Perhaps nothing frustrates appellate counsel more than discovering that a valid argument on appeal is foreclosed by trial counsel’s failure to properly raise the argument in the district court.

In today's ACT Brief, we explore how Bayesian approaches are powering studies in rare disease and pediatrics, a major public-private initiative is standardizing digital endpoints for regulatory ...

A multisite research team has issued ethical and policy recommendations for first-in-human clinical trials involving the transplantation of pig kidneys into humans. The first trial has been approved ...