For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat ...

Parathyroid hormone (PTH) is an 84 amino acid peptide that is secreted from the parathyroid glands in response to low blood calcium (Ca) levels. PTH is the principal regulator of blood Ca ...

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat ...

Orally disintegrating tablets offer numerous advantages compared with traditional tablets and capsules, and can be an effective solution for developing line extensions of currently marketed therapies.

Vardenafil (as HCl) 10mg; peppermint flavor; contains phenylalanine, sorbitol. The tissue concentration of cGMP is regulated by both the rates of synthesis and degradation via phosphodiesterases (PDEs ...

This article is part of PharmTech's supplement "API Synthesis and Formulation 2009." New drug-delivery technologies are often championed by contract manufacturing organizations. For new technologies ...

A hormone that helps people feel full after eating can be delivered into the bloodstream orally, according to new research from Syracuse University and Murdoch University. The hormone, called human ...

Patients with infective endocarditis on the left side of the heart are typically treated with intravenous antibiotic agents for up to 6 weeks. Whether a shift from intravenous to oral antibiotics once ...

Scientists have developed stable orally available cyclic peptides with a much higher bioavailability than current ones, virtually creating a generation of drugs that can target previously untreatable ...