In a world first, a research team at the University of Zurich has successfully treated mice carrying an inherited form of ...

Gene editing can repair a DNA error in mice that causes Dravet syndrome, a rare, incurable, and potentially deadly form of ...

What was achieved: Researchers corrected SCN1A mutations in mice using prime or base editing, reducing seizures and improving survival. Why it matters: These are the first demonstrations of directly ...

DNA has to be interpreted by cells. The letters or bases that make up genetic sequences are read in sets of three, and those three-base sequences are known as codons. Every codon encodes for one amino ...

The results, published May 5 in Nature Genetics, offer a new way to understand the molecular roots of cancer — an especially ...

Why do two people with the same cancer diagnosis—the same stage, the same cell type, and the same clinical profile—often have ...

Human cells usually contain two copies of most genes, one of which comes from the mother while the other comes from the father. It's long been thought that usually these two copies, or alleles of ...

New technology enables the insertion of a large segment of DNA into a genome, potentially expanding gene therapy treatment from cancellation of disease-causing mutations to replacement of an entire ...

Unexpected genetic benefit: A PTPN22 mutation tied to autoimmune diseases helped mice survive otherwise lethal coronavirus infection by enhancing natural killer cell function. Therapeutic potential: ...

The genomics of peppermint are not as fresh as their flavor but scientists from the University of California, Davis, have found a way to breathe new genetic variation into the species. The findings, ...