Researchers have developed an animal model that reproduces motor dysfunction and cerebellar neurodegeneration similar to that in spinocerebellar ataxia (SCA) by inhibiting chaperone-mediated autophagy ...
Non-motor symptoms are common in Parkinson disease (PD) and can appear before motor features and progress in both severity and diversity as the disease evolves. Both dopaminergic and non-dopaminergic ...
Researchers assessed whether early autonomic burden is associated with incident cognitive impairment in patients with prodromal Parkinson disease.