Researchers identified TBC1D9B as the off switch for ARL8B, a key regulator of lysosome positioning. This mechanism controls how cells adapt to nutrient stress and maintain metabolic balance.

Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or viral intruders. The PRRs forward the signals which results in the production ...

A team led by researchers at the University of Cologne has identified a protein called ANKIB1 that acts as a volume dial for the body’s frontline immune defenses, controlling how strongly cells ...

Researchers have identified a molecular "switch" that determines whether pancreatic cancer responds to or resists treatment, a finding that could make treatment-resistant tumors sensitive to drugs.

Scientists at Duke-NUS Medical School have identified a molecular "switch" that determines whether pancreatic cancer cells resist chemotherapy or respond to it—a finding that could help convert some ...

In the lab, new molecular on/off controls helped tame a toxic cancer drug and sped up a coronavirus diagnostic test by more than 70-fold. In a recent study, a new way to potentially control when drugs ...

Dental pulp injury caused by trauma or deep caries often leads to inflammation, tissue necrosis, and eventual loss of tooth ...

In biology, many RNA molecules act as sophisticated microscopic machines. Among them, riboswitches function as tiny biological sensors, changing their 3D shape upon binding to a specific metabolite.