Christian McCaffrey, who is fresh off a two-touchdown, 81-yard rushing effort in his last game, will lead the San Francisco ...

See who's in and who's out for the Week 12 matchup between the San Francisco 49ers and Carolina Panthers on November 24, 2025 ...

Christian McCaffrey forced 11 missed tackles, closing in on a new career high as his running keeps the 49ers’ offense on ...

In Week 11, Christian McCaffrey and the San Francisco 49ers play the Arizona Cardinals at 4:05 p.m. ET on Sunday at State Farm Stadium. McCaffrey, in his last game, posted this statline: 12 carries, ...

Brock Purdy threw three touchdown passes in his return from a toe injury, Christian McCaffrey had two rushing touchdowns and ...

Our best Panthers vs. 49ers player prop bets tonight include Christian McCaffrey and George Kittle to put up big numbers.

The 49ers know Brock Purdy is ready to return from his toe injury after missing San Francisco's last six games.

McCaffrey made history again in Monday’s game, prompting a big announcement from the NFL.

Sign up here to get it every weekday morning.🚨 Headlines 🏈 49ers 20, Panthers 9: The Niners struggled early but ultimately ...

Christian McCaffrey had a big night in his first game against Carolina since the Panthers traded him to San Francisco three ...

San Francisco 49ers running back Christian McCaffrey had a memorable performance against his former team, Carolina Panthers, ...