Explore 40 years of PCR history, from Kary Mullis’s invention story to the rise of digital PCR and how it revolutionized ...

In the summer of 1984, Henry Erlich, Glenn Horn, Randy Saiki, and myself were working on developing a DNA test for sickle cell anemia (SCA) at Cetus Corp. SCA is an autosomal dominant disease caused ...

I think all molecular biologists would recognize that the papers describing di-deoxy sequencing 1 and Kary Mullis' PCR technique 2 have changed the world of science profoundly. Mullis, a true "gonzo" ...

“What if I had not taken LSD ever; would I have still invented PCR? I don’t know. I doubt it. I seriously doubt it.” In 1986, biochemist Kary Mullis invented the polymerase chain reaction, a technique ...

In its formative years PCR and its intellectual possessors had to go through some legal wrangling over the originality of the technique. In point of fact, a 13-year earlier paper by Nobelist Gobind ...

Kary B. Mullis, a biochemist who won the 1993 Nobel Prize in chemistry for discovering a way to analyze DNA easily and cheaply and thus pave the way for major advances in medical diagnostics, ...