What drew you into gut microbiome research? I work with people who suffer from functional gastrointestinal disorders and have a myriad of symptoms, many which change over time. These diseases are ...
The intestinal epithelium of our body consists of a myriad of elongated villi microarchitectures which increase the total surface area of the inner wall for better absorption of digested nutrients.
Organ-on-a-chip maker Emulate has launched an upgraded offering for researchers studying inflammatory bowel disease with its tissue model that helps illustrate how immune cells are activated and ...
Microgravity culture during spaceflight enhances microbial infection process in 3D intestinal models
Infectious microbes have evolved sophisticated means to invade host cells, outwit the body's defenses and cause disease. While researchers have tried to puzzle out the complicated interactions between ...
Researchers demonstrate that under low fluid shear force conditions that simulate those found in microgravity culture during spaceflight, the foodborne pathogen Salmonella infects 3-D models of human ...
The gut microbiome is an important ecosystem of microbes that lives in each one of us, and its strength affects our overall health. However, the small intestine is an underappreciated part of the gut ...
NAMkind™ models have now been tested against a wide set of marketed ADC molecules, showing close correlation with clinical results in terms of the toxic impact in the liver and side effect profile in ...
The human intestine is made up of more than 40 square meters of tissue, with a multitude of folds on its internal surface that resemble valleys and mountain peaks in order to increase the absorption ...
In this White Paper, MatTek, now part of Sartorius, details a highly differentiated 3D small-intestine tissue model that uses primary human stem cells to provide a more accurate alternative to animal ...
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