Please provide your email address to receive an email when new articles are posted on . The FDA approved the first chimeric antigen receptor therapy in 2017, authorizing tisagenlecleucel for treatment ...

Researchers developed a humanized mouse model that better predicts how antibody drugs interact with the immune system. The ...

The candidate gene FKBP5 is involved in the development of stress-related psychiatric disorders. A few years ago, researchers at the MPI discovered that it is increasingly activated in the brains of ...

Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has ...

Immunotherapy harnesses a patient’s own immune system to combat cancer, with numerous benefits compared to conventional treatments such as chemotherapy and surgical removal. 1 Among different ...

A severe organ shortage plagues the progress of organ transplantation. One solution may be to generate human organs in other large mammals, however, that process is challenging. Now, researchers have ...

Why do 80 to 90% of people infected with COVID-19 experience only mild cases while 10 to 20% face more severe or life-threatening symptoms? Researchers in the lab of Yale’s Richard Flavell decided to ...

Figure 1: VIP protects against CD4 + T cell depletion in humanized mice resulting from challenge with CCR5-tropic or transmitted founder HIV strains. Figure 2: VIP prevents mucosal transmission of ...

Chinese military researchers were part of a project that created mice with “humanized” lungs — apparently to test the infectiousness of various viruses, according to a blockbuster report Thursday. The ...

In a bid to improve organ transplant options in the future, a team led by researchers at the Chinese Academy of Sciences has shown that it's possible to produce pig embryos containing "humanized" ...