Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

A lactic acid bacterium isolated from kimchi may help promote the removal of nanoplastics from the body by binding to them in ...

The human gastrointestinal tract is in a constant state of flux; it hosts a diverse and dynamic community of microbes known as the gut microbiome, and is constantly exposed to things in the ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

Intestine-Mimicking Cell Model Accurately Predicts Drug Toxicity KRIBBs hIEC model detects gastrointestinal toxicity with 94% accuracy, offering early prediction of drug side effects ...

Tuft cells are present throughout the intestinal tract as well as in many organs. Studies in mice have shown that when tuft cells sense the presence of pathogens, they signal to immune cells and to ...

Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured ...

Organ-Chips as a Platform for Studying Effects of Space on Human Enteric Physiology (Gut on Chip) examines the effect of microgravity and other space-related stress factors on biotechnology company ...

In a breakthrough for the advanced study of gut health, scientists have developed a 3D microscopic version of the human intestines condensed into a small chip about half the size of a five-cent coin.

While in vivo animal models are commonly employed for pharmacokinetic studies, they are often expensive, low in throughpu,t and typically fail to accurately replicate key characteristics of the human ...