Medical researchers have used animals, particularly mice, to mimic disease and study biological phenomena. The origin of mice as a standard model system for scientific research can extend back to the ...

The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained at early life, with implications for understanding and treating immunodeficiency, ...

Why does the same virus barely faze one person while sending another to the hospital? New research shows the answer lies in a molecular record etched into our immune cells by both our genes and our ...

Microbes have been engaged in an arms race with one another that goes back for millennia. While we have been able to reveal microbial defense systems like CRISPR, and we have been able to exploit some ...

How does the same infection, say the flu or a cold, give some people mild symptoms and leave others suffering? Why do people develop autoimmune diseases? And will we ever be able to predict when—and ...

An initiative partly funded by the Wellcome Trust Sanger Institute in the UK has moved further towards its goal of producing a 'human cell atlas' (HCA) to map every cell type in the human body.

A new method to keep human lymph node tissue alive and functioning outside the body for several days could give researchers a much clearer view of how our immune system responds to infections, ...

Mary E. Brunkow, Fred Ramsdell and Dr. Shimon Sakaguchi won the Nobel Prize in medicine on Monday for their discoveries concerning peripheral immune tolerance. Brunkow, 64, is a senior program manager ...

Human peadiatric thymus image from the IBEX protein multiplex (44 proteins on the same image) platform. Thymic epithelial cells are labeled with DEC205 (cyan), pan-cytokeratin (purple), keratin 5 (red ...