One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

The 4D map, which includes more than 140,000 folds and loops for every type of cell, illustrates how human DNA is organized not only in space but also in time. This information is crucial ...

A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop. Until recently, many fast-changing parts of the human genome remained ...

Cutting-edge DNA mapping technology identified new genetic information that can help researchers decipher more genetic diseases, a new study found. The research will be presented at the Pediatric ...

The ability to sequence and edit human DNA has revolutionized biomedicine. Now a new consortium wants to take the next step and build human genomes from scratch. The Human Genome Project was one of ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene activity—across 39 human cell types, revealing a complex landscape of ...

Researchers have used a new human reference genome, which includes many duplicated and repeat sequences left out of the original human genome draft, to identify genes that make the human brain ...