When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, ...

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

Explore the connections between the world of neuroscience and nuances of substance use disorders with our inaugural episode of In Such a Place. We’ll speak with Dr. Anna Radke, a leading expert in the ...

Why someone becomes addicted to a substance has long baffled scientists and philosophers. Now leading researchers are getting the clearest picture yet of how addiction works in the brain and body.

Ramirez is an associate professor of psychological and brain sciences at Boston University. When philosophers imagined the ship of Theseus, they asked: Can a vessel that has all its planks replaced ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

People struggling with many addictions, ranging from opioids to gambling, are reporting similar experiences in clinics, on ...