Natalie Holt sees reminders nearly everywhere of the serious toll a years-long syphilis outbreak has taken in South Dakota.

WATERTOWN — Watertown High School's volleyball team wasted no time making sure it would get the chance to play for an Eastern ...

South Dakota is home to Sioux Falls, one of the fastest-growing cities in the Midwest due to its incredible outdoor ...

Great Plains Lutheran's football team finished off another 4-4 regular season with a 44-0 win over Wilmot at Watertown ...

who made the earned 11-man all-conference honors for Dakota Hills the previous two seasons. Holien, Scharlemann and Ries are ...

Great Plains tribes are eager to capitalize on the burgeoning clean energy economy and are creating solar training programs.

Election Day showed varied appetite for cannabis legalization at ballot boxes across the historically-conservative Great Plains.

Track the latest US election North Dakota state results and view an interactive map with live updates on key races, including electoral vote counts and state-by-state breakdowns.

The National Indian Health Board has urged the U.S. Department of Health and Human Services to declare a public health emergency as an alarming syphilis outbreak, which disproportionately affects ...