This is a preview. Log in through your library . Abstract Insulin-activated glucose transport depends on the efficient sorting of facilitated hexose transporter isoforms to distinct subcellular ...
The glucose transporter GLUT4 facilitates insulin-stimulated glucose uptake into muscle and adipose tissue. Defects in glucose uptake represent an early step in the development of type 2 diabetes ...
Colon cancer risk is higher among type 2 diabetes patients Tests to identify the high risk group for colon cancer among diabetes patients can help in early diagnosis and treatment of the cancer ...
This is a preview. Log in through your library . Abstract The functional trafficking steps used by soluble NSF attachment protein receptor (SNARE) proteins have been difficult to establish because of ...
The protein Glut4 moves to the cell surface to help transport glucose from the blood into the cell after a meal. The left column shows total amount of Glut4 (green) in the cell and the right shows how ...
In normal myocytes, insulin treatment activates glucose uptake to the muscle by promoting the cell surface delivery of cytoplasmic storage vesicles that contain the glucose transporter GLUT4. Like ...
GLUT4 expression decreased in 19 pts with PMR, and 3 with SMD. Among 12 pts with exon 11 mutation, 11 had PMR, 1 SMD; among 5 pts with wild-type genotype, 4 had PMR, and 1 SMD. Conclusions: After IM ...
The common forms of type 2 diabetes are caused by a constellation of genetic and epigenetic factors and molecular changes related to diet; lifestyle, including lack of exercise and sleep; ...
B. Op 't Eijnde, B. Ursø, E.A. Richter, P.L. Greenhaff, P. Hespel ...
Insulin resistance has a causal role in type 2 diabetes. Serum levels of retinol-binding protein 4 (RBP4), a protein secreted by adipocytes, are increased in insulin-resistant states. Experiments in ...
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