Osaka, Japan – Tissues consist of a heterogenous mixture of different cell types, complicating our understanding of their biological functions and studies of disease. Now, a multi-institutional team ...

Electrospray ionization mass spectrometry (ESI-MS) has emerged as a pivotal analytical tool, enabling the gentle conversion of analytes in solution into gas-phase ions while minimising fragmentation.

In electrospray ionization (ESI), an electric potential is applied to a solution inside a capillary, producing a strong electric field at the spray capillary tip. That leads to the expulsion of an ...

Mass spectrometry (MS) is already perhaps the most popular analytical chemistry tool in drug discovery and development. Its use is ubiquitous in bioanalytical laboratories for drug and metabolite ...

Investigation of leptomeningeal disease in high grade glioma and characterization of molecular alterations. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not ...

Incidence and characteristics of breast cancer following a diagnosis of ductal carcinoma in situ. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This abstract does not include a ...

What are the ionization techniques for mass spectrometry? Mass spectrometry (MS) plays a vital role in many aspects of our lives, from diagnosing illness and detecting food contaminants to fighting ...

Researchers have developed a novel technology that allows the distribution of components within a single cell to be accurately detected and visualized. Positioning a t-SPESI (tapping-mode scanning ...