Researchers have identified a pathway that triggers an immune response in cells with defective DNA repair. In particular, the ...

The study focused on rare DNA damage-repair (DDR) disorders, including Ataxia-Telangiectasia (A-T) and Bloom syndrome. These ...

Learn more about a new experimental procedure that uses cancer cells’ DNA repair system against itself to make drug-resistant ...

The APOE2 gene variant protects against Alzheimer's by enhancing DNA repair and preventing neuronal senescence.

RNA’s Surprising Role in DNA Repair New insights could lead to improved treatments for cancer and other diseases. Francesca Storici and her research team discovered a surprising role for RNA in DNA ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal metabolic processes or external stressors such as radiation or chemical ...

DNA damage from inflammation outpaces the cells’ ability to self-repair. The finding, in human brain cells and mice, could ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...

Targeted DNA editing by CRISPR technology has great potential for applications in biotechnology and gene therapy. However, precise gene editing remains a challenge largely due to insufficient control ...