When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...

DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...

Scientists are exploring how DNA’s physical structure can store vast amounts of data and encode secure information.

DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study. DNA can mimic protein functions by folding into elaborate, three-dimensional ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Researchers at University of Tsukuba have uncovered a master transcriptional regulator that controls rhizobial symbiosis between plants and nitrogen-fixing bacteria. By identifying an amino acid motif ...

Picture in your mind a traditional “landline” telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in ...

Supercoiling and looping can transmit mechanical stress along the DNA backbone that can promote the separation of the strands of the double helix at specific distant sites, exposing the DNA bases, ...