Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

Typically in optical microscopy, the signal-to-noise ratio (SNR) is calculated to quantify the image contrast which indicates how well different regions of interest in the image can be differentiated.

All around us, a hidden world exists that remains invisible to the naked eye. The adult human body has between 28 and 36 trillion cells spread over 400 cell types, all too small to be seen, except for ...

Installed in a custom Titan Krios, the laser phase plate enhances motion correction, early‑frame recovery, and 3D classification and alignment.

The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...

Fifteen years ago, physicists worked out a method to increase image contrast by hitting the electron imaging beam with an ...

This article describes a six-inch wafer inspection microscope that provides automated, reproducible differential interference contrast (DIC) imaging, regardless of the user’s skill level. Wafer ...