In 2024, Professor Sebastian Kobold's research group at LMU University Hospital had already shown that the metabolite ...

Powerful white blood cells referred to as CD8 killer T cells enable the body to control infections and fight cancer. But when they become exhausted, they can become dysfunctional and ineffective.

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine ...

Northwestern Medicine scientists have identified the cellular mechanisms that cause immune cells to differentiate and ultimately lose function during viral infection, findings that could improve ...

CD7 is an attractive target for chimeric antigen receptor (CAR) T-cell therapy in relapsed or refractory T-cell acute lymphoblastic leukemia (ALL). Supportive results of first-in-human studies of base ...

A new predictive framework reprograms T cells to sustain immune memory while preserving their ability to fight cancer and infections.