ENPP1 is expressed in the region of scarring after injury to the heart. Cardiac muscle shown in red and ENPP1 in green demonstrates expression of ENPP1 in the region of scar formation.
The thick filament is a key component of sarcomeres, the basic units of striated muscle 1. Alterations in thick filament proteins are associated with familial hypertrophic cardiomyopathy and other ...
To save energy and precisely regulate cardiac contractility, cardiac muscle myosin heads are sequestered in an ‘off’ state that can be converted to an ‘on’ state when exertion is increased. The ‘off’ ...