A new strategy developed by Professor Nathan Gianneschi grabs cancer-driving proteins and directs them to the cell’s disposal ...

Many patients with metastatic cancers receive therapy that is initially highly effective, often resulting in complete remission. However, cancer cells have a remarkable capacity to evolve resistance ...

The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it. However, the molecular mechanisms ...

Crystalline polymers assembled inside tumor cell lysosomes rupture membranes, release iron, and trigger immune-activating ...

Scientists have uncovered an unexpected reason why some cancers return after initially responding to treatment.

Thanks to modern therapies, a cancer diagnosis is no longer an automatic death sentence. But many patients still suffer from unwanted side effects and limited efficacy. In a recent Bioconjugate ...

Scientists discovered that certain cancer cells use a low-level activation of a DNA-dismantling enzyme—normally seen in cell death—to survive treatment. Instead of dying, these “persister cells” ...

Researchers have resolved a 50-year-old scientific mystery by identifying the molecular mechanism that allows tissues to ...

As is often the case with cancer treatments, many patients are able to benefit from therapy for a time. Tumor activity ...