In a recent study published in the journal Nature, a large team of researchers from the United States (U.S.) used single-cell ribonucleic acid (RNA) sequencing combined with high-resolution ...

The adult mammalian heart bears limited regenerative capacity, resulting in the irreversible loss of cardiomyocytes post-cardiac injury, and often culminating in end-stage heart failure. Cardiomyocyte ...

CCN5 reduced cardiac cellular senescence in preclinical models of cardiovascular disease. Learn how this could shape ...

Atrial fibrillation (AF), the most common chronic cardiac arrhythmia in clinical practice, is very challenging to treat once ...

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is ...

Heart failure is the terminal stage of various cardiovascular diseases, usually characterized by pathological myocardial hypertrophy. So far, the pathogenesis of heart failure is not fully understood.

While current clinical trials for cardiac regeneration using induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) employ immunosuppressive regimens used in heart transplants, the precise ...

Study shows that cardiac spheroids, derived from human induced pluripotent stem cells, can be easily transported and injected into damaged areas of the heart to promote its regeneration and recovery ...