Mitochondrial biogenesis is known to accompany adipogenesis to complement ATP and acetyl-CoA required for lipogenesis. Here, we demonstrated that mitochondrial proteins such as ATP synthase α and β, ...

This is a preview. Log in through your library . Abstract Mitochondria have a characteristic ultrastructure with invaginations of the inner membrane called cristae that contain the protein complexes ...

This is a preview. Log in through your library . Abstract In a majority of living organisms, F o F₁ ATP synthase performs the fundamental process of ATP synthesis. Despite the simple net reaction ...

The inner mitochondrial membrane must be intact for oxidative phosphorylation to function properly. If the membrane is damaged or becomes leaky, protons can flow back into the matrix without passing ...

ATP, the compound essential for the functioning of photosynthetic organisms such as plants, algae, and cyanobacteria, is produced by an enzyme called “chloroplast ATP synthase” (CF o CF 1). To control ...

Each year, about 1,000 to 4,000 children in the United States are born with a mitochondrial disease. Many of these diseases are tied to a deficiency in ATP synthase thought to be triggered by ...

Scientists have solved the structure of mitochondrial ATP synthase, an enzyme that makes ATP, adenosine triphosphate, the major energy source of cells. A team of scientists headed by Rosalind Franklin ...

Oncotarget recently published "Targeting breast cancer metabolism with a novel inhibitor of mitochondrial ATP synthesis" by Kim, et al. which reported that the authors show that CADD522 inhibits ...

The experimental drug J147 is something of a modern elixir of life; it’s been shown to treat Alzheimer’s disease and reverse aging in mice and is almost ready for clinical trials in humans. Now, Salk ...