Central City is a city in Lawrence County, South Dakota, United States. The population was 93 at the 2020 census. Central City was founded in 1877. It was named after Central City, Colorado, by a settler from that community. It began as a mining town during the Black Hills Gold Rush days. There was once a quarrel over mining boundaries that resulted in a deliberate explosion of the nearby Comstock Mine and the death of one man. A miners' sit-down strike occurred and a cavalry unit from Fort Meade led by Seth Bullock was called in to end it.